Typhoid Fever
Causative organism:
Typhoid fever is caused by Salmonellae typhi (or salmonella paratyphi) bacteria.
Incidence:
Worldwide, typhoid fever affects more than 13 million people annually, with over 500,000 patients dying of the disease.
Mode of transmission:
Typhoid fever is contracted by the ingestion of contaminated food or water with the stool containing the bacteria from a case or asymptomatic carrier.
Symptoms:
- Poor appetite
- Headaches
- Generalized aches and pains
- Fever (reaching 39-40 degree celecius)
- Lethargy
- Diarrhea
Complications:
- Overwhelming infection
- Pneumonia
- Intestinal bleeding
- Intestinal perforation
Diagnosis:
Stool cultures are sensitive in the early and late stages of the disease but often need to be supplemented with blood cultures to make the definite diagnosis.
Prophylaxis and Treatment:
- Following the regular hygienic measures and avoiding drinking or ingestion of contaminated water or food with the bacteria
- The Typhoid vaccine could be given at any time after the age of 2 years and could be repeated each 2-3 years
- The definitive Treatment is by Antibiotic therapy (Chloramphenicol,3rd generation cephalosporin) the choice of antibiotic should be guided by the result of culture and sensitivity as there are some resistant strains.
For further information concerning the disease, vaccine and /or the treatment call 2356
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